Diffuse toxic goiter, or Graves' disease, Basedow - endocrine pathology, which is characterized by hyperactivity and hyperplasia of the thyroid gland.
The causes of the disease may be multiple factors.
Graves' disease: symptoms
The pathogenesis of the disease can lieviolation of immune surveillance in which the formation of autoantibodies with stimulating effect, which inevitably leads to thyroid hyperfunction with subsequent hyperplasia and hypertrophy. Also of great importance are genetic factors, chronic infection, intoxication, trauma.
The main symptoms of Graves' disease:
- Frequent changes nastroeniya-
- Tremor ruk-
- Increased utomlyaemost-
- Weight loss at elevated appetite-
- atrial aritmiya-
- Violation of the gastrointestinal treatise
- Pretibial miksadema when there is a thickening of the skin on the front of the foot and goleni-
- Reducing potentsii-
- Violation of the menstrual tsikla-
It should be noted, is not always in the presence of a diffusetoxic goiter occurs weight loss. Some patients gain a sufficient amount of extra padding, and Graves' disease is on the background of obesity.
Diagnosis of diffuse toxic goiter
Focus on examination gives the doctorendocrinologist. Ultrasound shows that the thyroid gland is a diffuse increase of the eyes is observed exophthalmos without trophic disorders. When you look down from the upper eyelids behind the eyeball movements. Neurological examination of the patient reveal instability Romberg position, hyperreflexia.
A blood test shows a significant decreasecholesterol, high iodine content, low level of triiodothyronine, thyroxine, and thyroid-stimulating hormone. At any questionable situation where accurate diagnosis is uncertain, the patient is prescribed conduct tests with thyrotropin.
If the level of thyroid-stimulating hormone during the trial does not rise, toxic diffuse goiter is confirmed.
Treatment of diffuse toxic goiter
As treatment or medication usesurgical methods. The doctor picks up the effective dose tireostatisticheskih drugs prescribed radioactive iodine. If the effect of substitution therapy is not available, worried atrial fibrillation, all of the other symptoms increase, shows the operation or radioiodine therapy.