The most progressive advancement in the field of medicine is still regarded as the discovery of penicillin. This drug, an antibiotic called later, completely turned the world.
Today, modern pharmacology has hundreds of species of antibiotics, which help to effectively treat a variety of complex infectious diseases.
Penicillin has passed?
Medicine from the time of penicillin went awayforward, creating a new generation of powerful drugs peers. The reason that modern doctors have to use powerful antimicrobial agents is that harmful bacteria have time to adapt to penicillin. Microbes have adapted and began to produce a special enzyme - penicillinase, which is capable of destroying antibiotics.
New generation antibiotics
Most of the newer antibiotics workselectively, t. e. their action is directed against one or two microbial species. Today in curative medicine widely used antibiotics of the fluoroquinolone, cephalosporin, imipenem, macrolides, penicillins. The most powerful antibiotics are broad-spectrum antibiotics that kill gram-positive and Gram and bacteria.
To this group belong to the most powerfulantibiotics with a broad spectrum of activity, working bactericidal. These drugs are well tolerated, having minimal side effects. Now the group has four generations of cephalosporins.
•; the first-generation drugs.
Excellent work against staph infections cefadroxil ( "Biodroksil", "Durotsef"), cefazolin ( "Kefzol", "Rizolin"), cephalexin ( "Ospeksin", "Sporideks").
•; second-generation drugs.
Medications prescribed to combat intestinal and Haemophilus influenzae, Klebsiella. This cefuroxime ( "Zinnat" "Ketotsef" "Aksetin" "Ketotsef"), cefaclor ( "Taratsef" "Vertsef").
•; third-generation drugs.
Well established in the treatment ofdiseases such as pyelonephritis, meningitis, pneumonia, abdominal, osteomyelitis infection. These include ceftazidime ( "Fotrazim" "Fortum"), ceftriaxone ( "Tortsef" "Lendatsin"), ceftazidime ( "Tsefobid" "Medotsef"), cefotaxime ( "Tsefosin" "Claforan").
•; fourth-generation product - the strongest of cephalosporins ( "Cefepime").
The range of their application is much wider than the previous group, at the same time more and list of side effects: dysbiosis, nephrotoxicity, neurotoxicity haematotoxicity.
Antibiotics are narrow applicationmacrolides that have proven themselves in the struggle against Gram-positive microorganisms. The action directed to macrolides Stops bacterial cell growth, while they do not inhibit the immune system.
For drugs in this group include "erythromycin""Spiramycin" "oleandomycin" "Clarithromycin", "azithromycin", "Josamycin" "Roxithromycin". The most powerful of macrolides considered "Josamycin" and "clarithromycin". These drugs are prescribed for the treatment of stomach ulcers, sinusitis, otitis, respiratory and chlamydial infections.