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How many minutes begins to act Analgin

After how many minutes begins to act Analgin

"Analgin" is a non-steroidal anti-inflammatory agent. It has analgesic, antipyretic effect.

The active ingredient of the drug - sodium metamizole.

How does "Analgin"

"Analgin" able to block cyclooxygenase -enzyme involved in the synthesis of prostaglandins (group of substances involved in the formation of painful and inflammatory processes). As a result, the process of the synthesis of prostaglandins, arachidonic acid, bradykinin is slowing, pain impulses are blocked, heat increases, body temperature drops.
"Analgin" is available in tablets, capsules(Solution for intramuscular and intravenous), rectal suppositories. Tablets, suppositories The drug takes effect within 15-30 minutes after application. The maximum concentration in the blood means there is an hour and a half after application. The injection of the drug will work in 10-20 minutes. Duration "Analgin" - 4-8 hours. The ingestion of the drug active ingredient 80-90% digested within the gastrointestinal tract, a small portion is associated with blood proteins, the main body is in a concentration in the unbound form.

Metamizole itself has no pharmacological effect therapeutic action develops after the transformation in the liver metabolite.

How to apply "Analgin"

"Analgin" is used in rheumatism, febrilestates, acute respiratory diseases, pain of various origins (neuralgia, neuritis, myositis, radiculitis). The drug is usually prescribed to 250-500 mg two or three times a day. The maximum allowable single dose - not more than 1 g daily - not more than 3 g
Intramuscular or intravenous agent usedwith strong pains 250-500 ml three times a day. Children under the age of one year drug administered by intramuscular injections two to three times per day, at a rate of five to ten milligrams per kilogram of body weight. Adults "Analgin" in rectal suppositories used in dosages 300 mg 650.1000. Rectal suppositories for children administered, given the disease and age. For children from six months to a year are recommended suppositories 100 mg, children between 1-3 years prescribe suppositories 200 mg, children 3-7 years light candles 200-400 mg, for children aged 8-14 years - 200-600 mg.

After rectal administration of the drug need to lie down for a while.

"Analgin" can have the following sideaction: skin rash, leukopenia, skin rash, fever, headache, dizziness. The drug is contraindicated in diseases of the blood, bone marrow suppression function during pregnancy and breastfeeding, in dysmenorrhea, liver, renal insufficiency, aspirin asthma, anemia.

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