Kawasaki's disease affects children of all races and nationalities, but most often occurs in Japanese. It can seriously complicate the work of the heart and blood vessels and lead to myocardial infarction.
Kawasaki disease is a rare disease, for the first timeDescribed in Japan. Affects children under 8 years, most often boys. Japanese children are much more prone to this ailment than children of other nationalities and races. Kawasaki disease causes acute systemic necrotizing vasculitis. In this case, large, medium and small arteries are affected.
Causes and Symptoms
The causes of the disease are not known to the end. Seasonal variability and cyclicity of the disease suggests its infectious nature, which is why it is associated with the effect of retrovirus, as the ailment occurs suddenly and affects children with weakened immunity. The disease begins acutely, causing an increase in body temperature, hyperemia conjunctiva, dry lips and mucous membranes of the mouth. Later the body of the baby is covered with polymorphic or scarlet-like rashes, the hands and feet swell. The child is fevering from 12 to 36 days. In the second week of the disease, the rash and conjunctivitis disappear, the lymph nodes return to their normal state, and the tongue acquires a crimson color, the fingers and toes are subjected to lamellar ecdysis.
The danger of this disease is that itGives a serious complication on the heart. The doctor can diagnose arthralgia, muffled heart tones, cardiomegaly, systolic murmur, and an increase in liver size. The involvement of the heart in the pathological process can occur in the early days of the disease or, conversely, after the crisis. In acute form of the disease in the myocardium (cardiac muscle), inflammation develops. Such a process often occurs without consequences, but sometimes congestive heart failure may occur. A weakened cardiac muscle can not effectively perform its work, causing fluid accumulation in the tissues and swelling.
In one case, out of five, heavyComplications of the heart and blood vessels. The walls of the latter lose their elasticity and elasticity, forming pockets - aneurysms. This leads to the formation of clots, and, as a consequence, myocardial infarction.
Treatment, above all, is aimed at protectingof cardio-vascular system. With Kawasaki's disease, aspirin remains an unchanged drug, which not only reduces heat, but also dilutes the blood, preventing the formation of clots and has a powerful anti-inflammatory effect. When coronary artery damage, "Acetylsalicylic acid" is administered in small doses for a long time. And although aspirin is not recommended for use in children under 12 years of age, with Kawasaki disease, such therapy is justified.
In addition, daily intravenousInjection of immunoglobulin for 5-7 days. This drug increases the passive immunity of the patient and his recovery. Recent research in the field of treatment of this disease has proved the effectiveness of the application of "Heparin" and regular physical education.