"Allopurinol" - the drug, which is taken at an elevated concentration of uric acid in the blood.
The tool removes the complications and pain, slow disease progression.
on the application of "Allopurinol" Instructions
"Allopurinol" administered in combination therapydiseases associated with hyperuricemia (high uric acid): urolithiasis, primary or secondary gout, urine acid nephropathy with renal insufficiency, a violation of purine metabolism in children. The drug is also prescribed in the case of primary and secondary hyperuricemia, which appears when:
- Extensive injuries,
- Enzyme disorders
- Therapy of corticosteroids,
- Radiation or cytostatic therapy of cancer.
"Allopurinol" should be taken after a meal in the following doses:
- Gout with mild symptoms, as well as recurrent kidney stones - 200-300 mg per day,
- With severe gout - 400-600 mg per day,
- Nephropathy for warning if necessary to make chemotherapy blood disorders - 600-800 mg per day for the first 2-3 days.
In case of adverse reactions from the gastrointestinal tract at doses greater than 300 mg of "Allopurinol" should be taken in parts.
Said dose may be taken once or divided into two parts. The minimum daily dose - 100-200 mg, the maximum - 800-900 mg.
Contraindications, side effects "Allopurinol"
"Allopurinol" is contraindicated in patients with renal andhepatic insufficiency, hypersensitivity, idiopathic hemochromatosis, asymptomatic hyperuricemia, acute attacks of gout, pregnancy and lactation. The drug is not indicated for children under 14 years, except for the enzymatic treatment of severe violations of cytostatic therapy of malignant tumors.
In the period of treatment with the use of alcohol is not allowed.
"Allopurinol" cautiously prescribed forchronic heart failure, diabetes, hypertension, renal insufficiency. The drug also should be given with caution in patients whose activities require fast psychomotor reactions and high concentration.
According to reviews in rare cases "Allopurinol" cancause the following side effects: nausea, vomiting, diarrhea, abdominal pain, stomatitis, jaundice, hepatitis, high blood pressure, muscle pain, joint pain, headaches, depression, drowsiness, loss of taste sensations, blurred vision, conjunctivitis, nephritis, edema , reduced potency, dehydration, abrasions, sore throat, nosebleeds, diabetes. Allergic symptoms: hives, itching and skin rashes, dermatitis, bronchospasm.