"Allopurinol" is a drug that is taken with an increased concentration of uric acid in the blood.
The drug eliminates complications and pain, slows the development of the disease.
Instructions for the use of "Allopurinol"
"Allopurinol" is prescribed in complex therapyDiseases accompanied by hyperuricemia (increased uric acid): urolithiasis, primary or secondary gout, uric acid nephropathy with kidney failure, violation of purine metabolism in children. The drug is also prescribed in the case of primary and secondary hyperuricemia, which occurs when:
- extensive injuries,
- enzymatic disorders,
- therapy with glucocorticosteroids,
- Radiation or cytostatic therapy of cancer.
"Allopurinol" should be taken after meals in the following doses:
- with a gout with mild symptoms, as well as with relapsing kidney stones - 200-300 mg per day,
- with severe gout - 400-600 mg per day,
- to prevent nephropathy, if you need to do chemotherapy for blood diseases - 600-800 mg per day in the first 2-3 days.
In case of negative reactions from the digestive tract at doses over 300 mg, "Allopurinol" should be taken in parts.
This dose can be taken at one time or divided into two parts. The minimum daily dose of the drug is 100-200 mg, the maximum dose is 800-900 mg.
Contraindications, side effects of "Allopurinol"
"Allopurinol" is contraindicated in renal andHepatic insufficiency, hypersensitivity, idiopathic hemochromatosis, asymptomatic hyperuricemia, acute gout attacks, pregnancy and lactation. The drug is not prescribed for children under 14 years, except for the treatment of severe enzyme disorders, cytostatic therapy of malignant tumors.
During the period of drug treatment, alcoholic beverages are not allowed.
Allopurinol is cautiously prescribed whenChronic heart failure, diabetes, arterial hypertension, renal failure. The drug should also be used with caution in patients whose activities require rapid psychomotor reactions and high concentration of attention.
According to reviews in rare cases, "Allopurinol" canCause the following side effects: nausea, vomiting, diarrhea, abdominal pain, stomatitis, jaundice, hepatitis, increased blood pressure, muscle aches, joints, headaches, depression, drowsiness, loss of taste, visual impairment, conjunctivitis, nephritis, swelling , Decreased potency, dehydration, furunculosis, tonsillitis, nosebleeds, diabetes mellitus. Possible allergic manifestations: urticaria, itching and rash of skin, dermatitis, bronchospasm.